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Ketoprofen

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Ketoprofen chemical structure
Ketoprofen
Systematic (IUPAC) name
2-(3-benzoylphenyl)propanoic acid
Identifiers
CAS number 22071-15-4
ATC code M01AE03 M01AE17, M02AA10
PubChem 3825
DrugBank APRD01059
Chemical data
Formula C16H14O3
Mol. weight 254.281 g/mol
Pharmacokinetic data
Protein binding 99%
Half life 2-2.5 hours

Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin.

Ketoprofen was available over-the-counter in the United States in the form of 12.5mg coated tablets (Orudis KT®), but the product has been discontinued. It is available by prescription as 25, 50, 75, 100, 150, and 200mg capsules.

Ketoprofen also comes in a 2,5% gel for topical application.

Brand names in the US are Orudis and Oruvail.


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